Design and synthesis of a novel DNA-encoded chemical library using Diels-Alder cycloadditions

F Buller, L Mannocci, Y Zhang, CE Dumelin…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 18, # 22 p. 5926 - 5931

Full Text: HTML

Citation Number: 57

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... The isolation of small organic molecules, capable of specific binding to proteins, is a central problem in chemistry, biology, and medicine. ... These hits are then selected for further optimization by medicinal chemistry. ...

Related Articles:

Derivatives of aryl amines containing the cytotoxic 1, 4-dioxo-2-butenyl pharmacophore

[Jha, Amitabh; Mukherjee, Chandrani; Prasad, Ashok K.; Parmar, Virinder S.; Vadaparti, Manjula; Das, Umashankar; De Clercq, Erik; Balzarini, Jan; Stables, James P.; Shrivastav, Anuraag; Sharma, Rajendra K.; Dimmock, Jonathan R. Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 5 p. 1510 - 1515]

Copper–phenanthroline catalysts for regioselective synthesis of pyrrolo [3′, 4′: 3, 4] pyrrolo [1, 2-a] furoquinolines/phenanthrolines and of pyrrolo [1, 2-a] …

[Beilstein Journal of Organic Chemistry, , vol. 10, p. 692 - 700]

Derivatives of aryl amines containing the cytotoxic 1, 4-dioxo-2-butenyl pharmacophore

[Jha, Amitabh; Mukherjee, Chandrani; Prasad, Ashok K.; Parmar, Virinder S.; Vadaparti, Manjula; Das, Umashankar; De Clercq, Erik; Balzarini, Jan; Stables, James P.; Shrivastav, Anuraag; Sharma, Rajendra K.; Dimmock, Jonathan R. Bioorganic and Medicinal Chemistry Letters, 2010 , vol. 20, # 5 p. 1510 - 1515]

Design and synthesis of a novel DNA-encoded chemical library using Diels-Alder cycloadditions

[Buller, Fabian; Mannocci, Luca; Zhang, Yixin; Dumelin, Christoph E.; Scheuermann, Joerg; Neri, Dario Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 22 p. 5926 - 5931]

Copper–phenanthroline catalysts for regioselective synthesis of pyrrolo [3′, 4′: 3, 4] pyrrolo [1, 2-a] furoquinolines/phenanthrolines and of pyrrolo [1, 2-a] …

[Paira, Rupankar; Anwar, Tarique; Banerjee, Maitreyee; Bharitkar, Yogesh P.; Mondal, Shyamal; Kundu, Sandip; Hazra, Abhijit; Maulik, Prakas R.; Mondal, Nirup B. Beilstein Journal of Organic Chemistry, 2014 , vol. 10, p. 692 - 700]

More Articles...