Tetrahedron

Synthesis and reactivity of lithium tri (quinolinyl) magnesates

S Dumouchel, F Mongin, F Trécourt, G Quéguiner

Index: Dumouchel, Sylvain; Mongin, Florence; Trecourt, Francois; Queguiner, Guy Tetrahedron, 2003 , vol. 59, # 43 p. 8629 - 8640

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Citation Number: 56

Abstract

2-, 3-and 4-Bromoquinolines were converted to the corresponding lithium tri (quinolinyl) magnesates at− 10° C when exposed to Bu3MgLi in THF. The resulting organomagnesium derivatives were quenched with various electrophiles or involved in metal-catalyzed coupling reactions with heteroaryl halides to afford functionalized quinolines.

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