Nucleosides, Nucleotides & Nucleic Acids 2010-02-01

An efficient deprotection of N-trimethylsilylethoxymethyl (SEM) groups from dinucleosides and dinucleotides.

Tilak Chandra, William E Broderick, Joan B Broderick

Index: Nucleosides Nucleotides Nucleic Acids 29(2) , 132-43, (2010)

Full Text: HTML

Abstract

A convenient and efficient method for deprotection of N-(trimethyl)silylethoxymethyl (SEM) groups from thymidine dinucleoside and dinucleotide has been achieved. The SEM groups were easily removed in excellent yields from protected nucleosides, dinucleosides, and dinucleotides.

Related Compounds

  • Tin(IV) chloride

Related Articles:

Novel styrylbenzene derivatives for detecting amyloid deposits.

2014-09-25

[Clin. Chim. Acta 436 , 27-34, (2014)]

Synthesis of multivalent silica nanoparticles combining both enthalpic and entropic patchiness.

2015-01-01

[Faraday Discuss. 181 , 139-46, (2015)]

A facile preparation of peracylated alpha-aldopyranosyl chlorides with thionyl chloride and tin tetrachloride.

2008-11-24

[Carbohydr. Res. 343(17) , 2989-91, (2008)]

SnCl(4)- and TiCl(4)-catalyzed anomerization of acylated O- and S-glycosides: analysis of factors that lead to higher α:β anomer ratios and reaction rates.

2010-10-15

[J. Org. Chem. 75(20) , 6747-55, (2010)]

SnCl4 · 5H2O-catalyzed synthesis of β-amino carbonyl compounds via a direct Mannich-type reaction.

2011-01-01

[Prep Biochem Biotechnol. 41(1) , 1-6, (2011)]

More Articles...