Journal of the American Chemical Society

Asymmetric synthesis of monosubstituted and. alpha.,. alpha.-disubstituted. alpha.-amino acids via diastereoselective glycine enolate alkylations

RM Williams, MN Im

Index: Williams; Im Journal of the American Chemical Society, 1991 , vol. 113, # 24 p. 9276 - 9286

Full Text: HTML

Citation Number: 241

Abstract

Nonproteinogenic, unnatural a-amino acids have increasingly attracted the attention of numerous disciplines in connection with the design and synthesis of enzyme inhibitors as potential constituents of pharmaceuticals, as optically active starting materials for a variety of synthetic applications, and for the study of enzymatic reaction mechanisms. As a consequence, numerous and versatile approaches to the synthesis of nonproteinogenic, ...

Related Articles:

The asymmetric synthesis of. alpha.-amino acids. Electrophilic azidation of chiral imide enolates, a practical approach to the synthesis of (R)-and (S)-. alpha.-azido …

[Evans, David A.; Britton, Thomas C.; Ellman, Jonathan A.; Dorow, Roberta L. Journal of the American Chemical Society, 1990 , vol. 112, # 10 p. 4011 - 4030]

Asymmetric synthesis of arylalanines via asymmetric aza-darzens (ADZ) reaction

[Maguire, Naomi E.; McLaren, Andrew B.; Sweeney Synlett, 2003 , # 12 p. 1898 - 1900]

Titanium chloride-mediated reactions of the silyl ketene acetals derived from N-methylephedrine esters: an asymmetric variant of the Mukaiyama reaction

[Gennari, Cesare; Colombo, Lino; Bertolini, Giorgio Journal of the American Chemical Society, 1986 , vol. 108, # 20 p. 6394 - 6395]

Palladium-catalyzed reactions in aqueous media. An efficient removal of allyloxycarbonyl protecting group from oxygen and nitrogen

[Genet, Jean Pierre; Blart, Errol; Savignac, Monique; Lemeune, Stephane; Paris, Jean-Marc Tetrahedron Letters, 1993 , vol. 34, # 26 p. 4189 - 4192]

Simple conversion of fully protected amino acids to zwitterions

[Tetrahedron Letters, , vol. 53, # 12 p. 1433 - 1434]

More Articles...