Synthesis of nitropolycyclic aromatic hydrocarbons with the substituent at the longest axis

…, D Herreno-Saenz, KH Huang, TM Heinze…

Index: Miller, Dwight W.; Herreno-Saenz, Diogenes; Huang, Kurt H.; Heinze, Thomas M.; Fu, Peter P. Journal of Organic Chemistry, 1992 , vol. 57, # 13 p. 3746 - 3748

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Citation Number: 16

Abstract

Nitropolycyclic aromatic hyrocarbons (nitro-PAHs) are environmental contaminants and are present in the food hai in.^-^ Since many nitro-PAHs are metabolized to highly mutagenic and tumorigenic metabolites by mammalian and/or bacterial enzymes, there is concern regarding possible adverse human health effects from exposure to these compounds. We have been interested in structure-activity relationships as a means of utilizing the ...

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