Bioorganic & Medicinal Chemistry Letters 2001-07-09

A mechanism-based affinity-labeling agent for possible use in isolating N-acetylglucosaminidase.

M Ichikawa, Y Ichikawa

Index: Bioorg. Med. Chem. Lett. 11 , 1769-1773, (2001)

Full Text: HTML

Abstract

We have prepared several mechanism-based affinity-labeling agents for possible use in isolating N-acetylglucosaminidase, in which an N-acetylglucosamine is linked to an o-monofluoro- or difluoro-methyl phenoxy glycoside with or without a cleavable disulfide group in the tether to biotin.

Related Compounds

  • NHS-SS-(+)-Biot...

Related Articles:

Chemical probes of extended biological structures: synthesis and properties of the cleavable protein cross-linking reagent [35S]dithiobis(succinimidyl propionate).

1976-06-14

[J. Mol. Biol. 104 , 243-261, (1976)]

A dominant linear B-cell epitope of ricin A-chain is the target of a neutralizing antibody response in Hodgkin's lymphoma patients treated with an anti-CD25 immunotoxin.

2004-05-01

[Clin. Exp. Immunol. 136 , 365-372, (2004)]

A reagent for covalently attaching biotin to proteins via a cleavable connector arm.

1982-10-01

[Arch. Biochem. Biophys. 218 , 101-108, (1982)]

More Articles...