The Journal of organic chemistry

Copper-catalyzed synthesis of benzoxazoles via a regioselective C− H functionalization/C− O bond formation under an air atmosphere

S Ueda, H Nagasawa

Index: Ueda, Satoshi; Nagasawa, Hideko Journal of Organic Chemistry, 2009 , vol. 74, # 11 p. 4272 - 4277

Full Text: HTML

Citation Number: 127

Abstract

An efficient method for the synthesis of functionalized benzoxazoles is described that involves a copper (II)-catalyzed regioselective C− H functionalization/C− O bond formation protocol. The use of dichlorobenzene as a solvent at 160° C allows the use of air as the terminal oxidant in the catalytic synthesis of benzoxazoles in a process that has high functional group tolerance. The presence of a directing group at the meta position ...

Related Articles:

A green route for the synthesis of 2-substituted benzoxazole derivatives catalyzed by Al 3+-exchanged K10 clay

[Suresh, Dhanusu; Dhakshinamoorthy, Amarajothi; Pitchumani, Kasi Tetrahedron Letters, 2013 , vol. 54, # 48 p. 6415 - 6419]

Poly (ethylene glycol)-bound sulphonic acid as a novel catalyst for synthesis of benzoxazoles

[Chikhale, Rupesh V.; Pant, Amit M.; Menghani, Sunil S.; Wadibhasme, Pankaj G.; Khedekar, Pramod B. South African Journal of Chemistry, 2013 , vol. 66, p. 254 - 262]

Direct arylation of benzoxazole C–H bonds with iodobenzene diacetates

[Yu, Peng; Zhang, Guangyou; Chen, Fan; Cheng, Jiang Tetrahedron Letters, 2012 , vol. 53, # 34 p. 4588 - 4590]

Parallel synthesis of a library of benzoxazoles and benzothiazoles using ligand-accelerated copper-catalyzed cyclizations of ortho-halobenzanilides

[Evindar, Ghotas; Batey, Robert A. Journal of Organic Chemistry, 2006 , vol. 71, # 5 p. 1802 - 1808]

A highly efficient palladium-catalyzed desulfitative arylation of azoles with sodium arylsulfinates

[Wang, Min; Li, Dengke; Zhou, Wei; Wang, Lei Tetrahedron, 2012 , vol. 68, # 7 p. 1926 - 1930]

More Articles...