Archiv der Pharmazie (Weinheim) 2006-09-01

Chromium(III) complexes of D-glucosaminic acid and their effect on decreasing blood sugar in vivo.

Sheng-Ju Ou, Guang Chen, Zhi-Hua Lin, Zhi-Ping Bai, Chun-Ying Duan, Cai-Ping Mao

Index: Arch. Pharm. (Weinheim) 339(9) , 527-30, (2006)

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Abstract

Two chromium(III) complexes of glucosaminic acid were synthesized by neutralization and exchange reaction. The formation of 1 : 1 and 2 : 3 (Cr : glucosaminate) complexes was confirmed by elemental analyses and spectroscopic studies. The effect of the complexes on decreasing blood sugar was investigated on type-2 diabetes model rats induced by tetraoxypyrimidine. The results indicated that the effect on decreasing blood sugar was comparable to that of picolinate chromium complex (Cr(pic)(3)) currently used world wide.

Related Compounds

  • 6,6-di(ethylthio)h...
  • D-Glucosamic acid

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