Synthetic Communications

HClO4-SiO2 as an Efficient and Recyclable Catalyst for the Synthesis of Amide Derivatives

W Song, L Ma, L Hu

Index: Song, Weibin; Ma, Lei; Hu, Lihong Synthetic Communications, 2011 , vol. 41, # 21 p. 3186 - 3196

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Citation Number: 3

Abstract

Abstract An efficient and clean procedure for amide alkylation is reported by direct condensation of equimolar amounts of benzylic and allylic alcohols with primary amides in the presence of silica perchloric acid (HClO4-SiO2). The direct condensation of secondary