Journal of Organic Chemistry 2007-02-16

Syntheses of novel chiral sulfinamido ligands and their applications in diethylzinc additions to aldehydes.

Zhiyan Huang, Hongshan Lai, Yong Qin

Index: J. Org. Chem. 72(4) , 1373-8, (2007)

Full Text: HTML

Abstract

A novel class of sulfinamido alcohol ligands 1-6 was synthesized from (S)-tert-butanesulfinamide. These ligands showed excellent catalytic activities and enantiomeric selectivities in asymmetric additions of diethylzinc to aromatic aldehydes.

Related Compounds

  • Diethylzinc

Related Articles:

Copper-catalyzed asymmetric conjugate addition of diethylzinc to alpha,beta-unsaturated imines derived from alpha-aminoacids. Enantioselective synthesis of gamma-substituted alpha-dehydroaminoesters.

2006-11-09

[Org. Lett. 8 , 5405, (2006)]

(R)-(+)-Binol-functionalized mesoporous organosilica as a highly efficient pre-chiral catalyst for asymmetric catalysis.

2010-05-03

[Chem. Asian J. 5(5) , 1232-9, (2010)]

Highly enantioselective addition of terminal alkynes to aldehydes catalyzed by a new chiral beta-sulfonamide alcohol/Ti(OiPr)4/Et2Zn/R3N catalyst system.

2009-02-01

[Chirality 21(2) , 316-23, (2009)]

Enantioselective Reformatsky reaction of ethyl iododifluoroacetate with ketones.

2012-04-28

[Org. Biomol. Chem. 10(16) , 3332-42, (2012)]

Efficient chirality switching in the addition of diethylzinc to aldehydes in the presence of simple chiral alpha-amino amides.

2007-01-01

[Angew. Chem. Int. Ed. Engl. 46(47) , 9002-5, (2007)]

More Articles...