Synthetic Communications

Facile, Environmentally Friendly Synthesis of Benzaldehyde and Phenylacetaldehyde Analogs from Readily Available Toluene Derivatives

L Dai, J Yu, Y Chen, S Yu

Index: Dai, Liyan; Yu, Jie; Chen, Yingqi; Yu, Shichao Synthetic Communications, 2011 , vol. 41, # 20 p. 3078 - 3084

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Abstract

Abstract A facile environmentally friendly synthesis of bezaldehyde and phenylacetaldehyde analogs from readily available toluene derivatives is described. Oxidation of the styrylamines by H2O2 affords benzaldehydes in moderate yields, while the hydrolysis of styrylamines afforded phenylacetaldehyde analogs in good yields.

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