Tetrahedron letters

An expeditious synthesis of cyclic imides

N Flaih, C Pham-Huy, H Galons

Index: Flaih, Nazar; Pham-Huy, Chuong; Galons, Herve Tetrahedron Letters, 1999 , vol. 40, # 19 p. 3697 - 3698

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Citation Number: 27

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Trifluoroacetamide was reacted with diacids in the presence of N-ethyl-N-dimethyl-aminopropylcarbodiimide and of 1-hydroxybenzotriazole to afford cyclic imides of different ring size, providing a single step asymmetric synthesis of thalidomide. ... A one-step general synthesis of cyclic imides.

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