Journal of medicinal chemistry

Derivatives of Fluorene. XVIII. New Halogenofluorenes. I. Potential Antitumor Agents1, 2

HL Pan, TL Fletcher

Index: Pan,H.-L.; Fletcher,T.L. J. Med. Chem., 1964 , vol. 7, p. 31 - 38

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Citation Number: 13

Abstract

A number of new halogenofluorenes have been prepared and characterized. Chlorination of K-2-fluorenylacetamide and 5-2-(9-oxofluoreny1) acetamide and some of their derivatives has been studied. With excess chlorine Y-2-fluorenylacetamide and 5-2-(7-chlorofluoreny1) acetamide give N-2-(1, 3, 4 (?), 7-tetrachlorofluoren~~ l)-acetamide3 (I), whereas? J-2-(6- chlorofluorenyl)-(LVII), and N-2-(6, 7-dichlorofluorenyl) aretamide (LXJ'III) give K-2-(1, 3, 4 ...

A Convenient Route to 3, 6-Diaminofluoren-9-ones

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The Constitution of the Isomeric Dichlorofluorenone Carboxylic Acids Formed by the Action of Sulfuric Acid on 3, 3'-Dichlorodiphenic Acid

[Huntress; Atkinson Journal of the American Chemical Society, 1936 , vol. 58, p. 1514,1516]

Dications of fluorenylidenes. The effect of substituent electronegativity and position on the antiaromaticity of substituted tetrabenzo [5.5] fulvalene dications

[Levy, Amalia; Rakowitz, Amber; Mills, Nancy S. Journal of Organic Chemistry, 2003 , vol. 68, # 10 p. 3990 - 3998]