Nucleic Acids Symposium Series 1995-01-01

Lithiation-based silylation and stannylation of 6-chloro-9-(beta-D-ribofuranosyl)purine.

K Katoh, H Hayakawa, H Tanaka, H Kumamoto, T Miyasaka

Index: Nucleic Acids Symp. Ser. (34) , 155-6, (1995)

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Abstract

Reaction of the lithiated species of 9-(2,3,5-tris-O-tert-butyldimethylsilyl-beta-D-ribofuranosyl)-6-chloropu rine with Me3SiCl or Bu3SnCl was found to furnish the corresponding C-2 substituted product, as a result of silyl or stannyl migration from C-8 to C-2 position.

Related Compounds

  • 6-Chloropurineribo...

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