China Journal of Chinese Materia Medica 2011-05-01

[Alkaloids and anthraquinones from branches and leaves of uvaria kurzii].

Ziming Lv, Qingjian Zhang, Ruoyun Chen, Dequan Yu

Index: Zhongguo Zhong Yao Za Zhi 36(9) , 1190-2, (2011)

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Abstract

To investigate the chemical constituents of the branches and leaves of Uvaria kurzii.The compounds were isolated and purified by silica gel and Sephadex LH-20 column chromatographic methods. Their chemical structures were elucidated on the basis of physicochemical properties and spectral data.Nine compounds were isolated and identified as: bidebiline A(1), annobraine (2), oxoputerine (3), atherospermidine (4), liriodenine (5), physcion (6), questin (7), rubiadin 3-methyl ether (8), emodin (9).Compound 1-4, 6-9 were isolated from the genus Uvaria for the first time. Compound 3-5 showed inhabitation activities against tumor cell lines A549, Bel7402, BGC823, HCT-8, A2780, respectively.

Related Compounds

  • Rubiadin
  • Physcion

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