Regioselective synthesis of halohydrin esters from epoxides: reaction with acyl halides and rhodium-catalyzed three-component coupling reaction with alkyl halides …

K Nakano, S Kodama, Y Permana…

Index: Nakano, Koji; Kodama, Shunsuke; Permana, Yessi; Nozaki, Kyoko Chemical Communications, 2009 , # 45 p. 6970 - 6972

Full Text: HTML

Citation Number: 5

Abstract

Halohydrin esters can be used as building blocks for the synthesis of lipids 1 and biologically active compounds. 2 One of the common synthetic strategies for them is the conversion of 1,2-diols. 3 Another class of powerful synthetic strategies includes using epoxides as a starting material. For example, epoxides can be transformed into halohydrin esters via a two-step procedure in one-pot: (i) the ring-opening by halogen nucleophiles and (ii) the subsequent ...

Related Articles:

Reaction of epoxides with chlorocarbonylated compounds catalyzed by hexaalkylguanidinium chloride

[Gros, P.; Perchec, P. Le; Senet, J. P. Journal of Organic Chemistry, 1994 , vol. 59, # 17 p. 4925 - 4930]

A Cheap, Simple, and Versatile Method for Acetylation of Alcohols and Phenols and Selective Deprotection of Aromatic Acetates Under Solvent??Free Condition

[Rajabi, Fatemeh; Saidi, Mohammad R. Synthetic Communications, 2005 , vol. 35, # 3 p. 483 - 491]

Use of Alkene Chloronium Intermediates in Organic Synthesis. Two New Reactions of Alkene Chloronium Ions

[Sumrell,G. et al. Journal of Organic Chemistry, 1965 , vol. 30, p. 84 - 88]

Use of Alkene Chloronium Intermediates in Organic Synthesis. Two New Reactions of Alkene Chloronium Ions

[Sumrell,G. et al. Journal of Organic Chemistry, 1965 , vol. 30, p. 84 - 88]

Use of Alkene Chloronium Intermediates in Organic Synthesis. Two New Reactions of Alkene Chloronium Ions

[Sumrell,G. et al. Journal of Organic Chemistry, 1965 , vol. 30, p. 84 - 88]

More Articles...