Pfluegers Archiv/European Journal of Physiology 1981-04-01

A liquid ion-exchanger alternative to KCl for filling intracellular reference microelectrodes.

R C Thomas, C J Cohen

Index: Pflugers Arch. 390(1) , 96-8, (1981)

Full Text: HTML

Abstract

We have developed a filling solution for silanised microelectrodes consisting of potassium tetrakis (p-chlorophenyl) borate in octanol. Microelectrodes filled with this reference liquid ion-exchanger (RLIE) have equal selectivities to Na and K, and give the same membrane potential as do KCl-filled microelectrodes. The RLIE microelectrodes are more stable, less damaging to the cell membrane and do not leak Cl- ions. Their high resistance, however, makes them unsuitable for recording rapid potential changes or for passing current.

Related Compounds

  • Potassium tetrakis...

Related Articles:

Novel organic solvents for electrochemistry at the liquid/liquid interface.

2015-03-21

[Analyst 140(6) , 1947-54, (2015)]

Ionophore-based potentiometric sensors for the flow-injection determination of promethazine hydrochloride in pharmaceutical formulations and human urine.

2011-01-01

[Sensors (Basel.) 11(1) , 1028-42, (2011)]

Organic cation transport by Malpighian tubules of Drosophila melanogaster: application of two novel electrophysiological methods.

2004-05-01

[J. Exp. Biol. 207(Pt 12) , 2173-84, (2004)]

A novel potentiometric approach for detection of beta-adrenergics and beta-adrenolytics in high-performance liquid chromatography.

2003-08-01

[Il Farmaco 58(8) , 591-603, (2003)]

A chronoamperometric method to estimate changes in the membrane composition of ion-selective membranes.

2001-10-01

[Anal. Chem. 73(19) , 4599-606, (2001)]

More Articles...