Journal of Organic Chemistry 2003-02-21

Catalytic carbonylation of functionalized diamines: application to the core structure of DMP 323 and DMP 450.

Keisha-Gay Hylton, A Denise Main, Lisa McElwee-White

Index: J. Org. Chem. 68(4) , 1615-7, (2003)

Full Text: HTML

Abstract

W(CO)(6)-catalyzed carbonylation provides an alternative to phosgene or phosgene derivatives such as 1,1-carbonyldiimidazole (CDI) for the conversion of amines to ureas. As an illustration, the core structure of the HIV protease inhibitors DMP 323 and DMP 450 has been prepared by catalytic carbonylation of diamine intermediates from the original syntheses.

Related Compounds

  • Carbon monooxide-t...

Related Articles:

Surfactant-free synthesis of plasmonic tungsten oxide nanowires with visible-light-enhanced hydrogen generation from ammonia borane.

2015-06-01

[Chem. Asian J. 10 , 1291-4, (2015)]

Highly scalable, atomically thin WSe2 grown via metal-organic chemical vapor deposition.

2015-02-24

[ACS Nano 9(2) , 2080-7, (2015)]

The transient electrical conductivity of W-based electron-beam-induced deposits during growth, irradiation and exposure to air.

2009-05-13

[Nanotechnology 20(19) , 195301, (2009)]

Millisecond pulsed radio frequency glow discharge time of flight mass spectrometry: temporal and spatial variations in molecular energetics.

2004-01-01

[J. Am. Soc. Mass Spectrom. 15(1) , 87-102, (2004)]

Mechanism of W(CO)6 sonolysis in diphenylmethane.

2012-05-01

[Ultrason. Sonochem. 19(3) , 498-502, (2012)]

More Articles...