Journal of Physical Chemistry B 2005-09-15

Studies on electrochemical oxidation mechanisms of polyamides containing N-methylpyrrole and N-methylimidazole by electrospray ionization tandem mass spectrometry.

Zhonghua Ji, Jingjian Li, Jiang Zhou, Limei Hui, Gu Yuan, Shengmin Cai

Index: J. Phys. Chem. B 109(36) , 17162-8, (2005)

Full Text: HTML

Abstract

Electrochemical oxidization mechanism of polyamides containing N-methylpyrrole and N-methylimidazole was investigated by electrospray ionization tandem mass spectrometry (ESI-MS(n)). The spectra of the oxidization products unambiguously revealed that one or two oxygen atoms are added to the polyamide after the bulk electrolysis. It was found that electrochemical oxidation preferably takes place on the imidazole ring of the polyamide with both imidazole and pyrrole to produce a carbonyl group on the rings. ESI tandem mass spectrometry has proven to be an excellent method for the structural identification of electrochemical oxidation products of DNA-recognizing polyamides.

Related Compounds

  • 1-Methylpyrrole

Related Articles:

New insights on the photodissociation of N-methylpyrrole: the role of stereoelectronic effects.

2009-12-31

[J. Phys. Chem. A 113(52) , 14554-8, (2009)]

Investigation of non-covalent complexes of HIV-1 promoter DNA and polyamides containing N-methylpyrrole by electrospray ionization mass spectrometry.

2006-01-01

[Rapid Commun. Mass Spectrom. 20(11) , 1736-40, (2006)]

Analysis of noncovalent complexes between human telomeric DNA and polyamides containing N-methylpyrrole and N-methylimidazole by using electrospray ionization mass spectrometry.

2005-02-04

[Chemistry 11(4) , 1157-62, (2005)]

Investigation of noncovalent complexes between beta-cyclodextrin and polyamide acids containing N-methylpyrrole and N-methylimidazole by electrospray ionization mass spectrometry.

2006-01-01

[J. Am. Soc. Mass Spectrom. 17(1) , 9-14, (2006)]

A new method for the determination of the relative affinity of a ligand against various DNA sequences by electrospray ionization mass spectrometry. Application to a polyamide minor groove binder.

2009-08-01

[J. Mass Spectrom. 44(8) , 1171-81, (2009)]

More Articles...