Journal of Peptide Research 2004-03-01

3-Azido-aspartic acid derivatives - orthogonally protected precursors for the stereoselective incorporation of 2,3-diaminosuccinic acid into peptide structures.

C Riemer, T Bayer, H Schmitt, H Kessler

Index: J. Pept. Res. 63(3) , 196-9, (2004)

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Abstract

The stereoselective synthesis of orthogonally protected 3-azido aspartic acid derivatives is described. The convenience of their application as 2,3-diaminosuccinic acid in peptide chemistry was demonstrated by the incorporation of the nonproteinogenic diamino diacid as a cystine-substitute into the core structure of somatostatin.

Related Compounds

  • meso-2 3-diaminosu...

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