Organic & Biomolecular Chemistry 2012-11-28

Metal-free catalyzed oxidative trimerization of indoles by using TEMPO in air: a biomimetic approach to 2-(1H-indol-3-yl)-2,3'-biindolin-3-ones.

Wen-Bing Qin, Qiong Chang, Yun-Hong Bao, Ning Wang, Zheng-Wang Chen, Liang-Xian Liu

Index: Org. Biomol. Chem. 10(44) , 8814-21, (2012)

Full Text: HTML

Abstract

A simple, convenient and efficient metal-free catalyzed oxidative trimeric reaction of indoles toward a variety of 2-(1H-indol-3-yl)-2,3'-biindolin-3-one derivatives in moderate to excellent yields has been developed. This transformation proceeds via a tandem oxidative homocoupling reaction by using TEMPO in air as an environmentally benign oxidant. This methodology provides an alternative approach for the direct generation of all-carbon quaternary centers at the C3 position of indoles.

Related Compounds

  • 2,2,6,6-Tetramethy...
  • Indoline

Related Articles:

Chemical isolation and characterization of different cellulose nanofibers from cotton stalks.

2015-12-10

[Carbohydr. Polym. 134 , 581-9, (2015)]

Efficient and simple approaches towards direct oxidative esterification of alcohols.

2014-11-17

[Chemistry 20(47) , 15618-24, (2014)]

Nanofibrillated Cellulose and Copper Nanoparticles Embedded in Polyvinyl Alcohol Films for Antimicrobial Applications.

2015-01-01

[Biomed Res. Int. 2015 , 456834, (2015)]

The plasma proteomic signature as a strategic tool for early diagnosis of acute coronary syndrome.

2014-01-01

[Proteome Sci. 12 , 43, (2015)]

Heart mitochondrial proteome study elucidates changes in cardiac energy metabolism and antioxidant PRDX3 in human dilated cardiomyopathy.

2015-01-01

[PLoS ONE 9(11) , e112971, (2014)]

More Articles...