Synlett

Gold (III)-catalyzed 1, 4-nucleophilic addition: facile approach to prepare 2-amino-1, 4-naphthalenedione and 6-amino-5, 8-quinolinedione derivatives

C Jiang, S Wang

Index: Jiang, Chunhui; Wang, Shaozhong Synlett, 2009 , # 7 p. 1099 - 1102

Full Text: HTML

Citation Number: 12

Abstract

Abstract An efficient approach is developed to prepare different 2-amino-1, 4- naphthalenedione and 6-amino-5, 8-quinolinedione derivatives regioselectively by Au (III)- catalyzed 1, 4-nucleophilic addition and subsequent oxidation. A wide variety of primary, secondary, and aromatic amines, as well as allylamine and 2-butynylamine are well tolerated under the mild conditions to give products in moderate to good yields.