Graphite Oxide as an Auto??Tandem Oxidation–Hydration–Aldol Coupling Catalyst

HP Jia, DR Dreyer, CW Bielawski

Index: Jia, Hong-Peng; Dreyer, Daniel R.; Bielawski, Christopher W. Advanced Synthesis and Catalysis, 2011 , vol. 353, # 4 p. 528 - 532

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Citation Number: 113

Abstract

Abstract Graphite oxide (GO) was found to function as an auto-tandem oxidation–hydration– aldol coupling catalyst for the formation of chalcones in a single reaction vessel. Various alkynes or alcohols were hydrated or oxidized in situ to their corresponding methyl ketones or aldehydes, respectively, which underwent a subsequent Claisen–Schmidt condensation. Each of the aforementioned reactions proceeded in the absence of metals (confirmed by ...