Organic & Biomolecular Chemistry 2008-06-07

The aerobic oxidation of alcohols with a ruthenium porphyrin catalyst in organic and fluorinated solvents.

Vasily N Korotchenko, Kay Severin, Michel R Gagné

Index: Org. Biomol. Chem. 6(11) , 1961-5, (2008)

Full Text: HTML

Abstract

Carbonylruthenium tetrakis(pentafluorophenyl)porphyrin Ru(TPFPP)(CO) was utilized for the aerobic oxidation of alcohols. The in situ activation of the catalyst with mCPBA provided a species capable of catalyzing the oxidation of alcohols with molecular oxygen. The choice of solvent and additive was crucial to obtaining high activity and selectivity. Secondary aromatic alcohols were oxidized in the presence of the ruthenium porphyrin and tetrabutyl ammonium hydroxide in the solvent bromotrichloromethane, enabling high yields to be achieved (up to 99%). Alternatively, alcohols could be oxidized in perfluoro(methyldecalin) with the ruthenium porphyrin at higher temperatures (140 degrees C) and elevated oxygen pressures (50 psi).

Related Compounds

  • Perfluoro(Methyld...

Related Articles:

[Biological fixation of nitrogen and growth of bacteria of the genus Azotobacter in liquid media in the presence of perfluorocarbons].

2007-01-01

[Prikl. Biokhim. Mikrobiol. 43(4) , 443-9, (2007)]

[Effect of perfluorodecalin, carbogal, and perfluoromethyldecalin on growth and ice-forming activity of bacteria].

2006-01-01

[Mikrobiologiia 75(3) , 371-6, (2006)]

Synthesis of composite emulsions and complex foams with the use of microfluidic flow-focusing devices.

2007-10-01

[Small 3(10) , 1792-802, (2007)]

A synthetic emulsion reproduces the functional properties of pulmonary surfactant.

1983-03-22

[Biochim. Biophys. Acta 751(1) , 74-80, (1983)]

Perfluoro-1-methyldecalin as a potential oxygen carrier with fluid scleral lenses.

1985-06-01

[Curr. Eye Res. 4(6) , 732-3, (1985)]

More Articles...