Clinical Toxicology 2011-03-01

Inadvertent poisoning of seven teenagers with monosodium methanearsonate.

Robert D Cox, Jeffrey Orledge

Index: Clin. Toxicol. (Phila.) 49(3) , 167-70, (2011)

Full Text: HTML

Abstract

Monosodium methanearsonate (MSMA) is an organo-arsenic containing herbicide. There is scant information available concerning the toxicity of this chemical in humans.Seven male teenagers, 15-18 years of age, inadvertently used a MSMA herbicide as cooking oil to fry fish. All had early gastrointestinal (GI) symptoms. Whole blood arsenic concentrations ranged from 348 to 613 μg/L and initial urine levels ranged from 81 400 to 226 300 μg-arsenic/g-creatinine. They were all treated with dimercaprol for 1 day and succimer for 19 days. They were followed for 15-months and had no evidence of any serious toxicity.MSMA produces early GI symptoms and very high levels of arsenic in blood and urine, but no evidence of long-term toxicity.

Related Compounds

  • dimercaprol
  • Sodium methanearso...

Related Articles:

Nox2-dependent glutathionylation of endothelial NOS leads to uncoupled superoxide production and endothelial barrier dysfunction in acute lung injury.

2014-12-15

[Am. J. Physiol. Lung Cell. Mol. Physiol. 307(12) , L987-97, (2014)]

Nicotinamide exacerbates hypoxemia in ventilator-induced lung injury independent of neutrophil infiltration.

2015-01-01

[PLoS ONE 10(4) , e0123460, (2015)]

Safety and biocompatibility of carbohydrate-functionalized polyanhydride nanoparticles.

2015-01-01

[AAPS J. 17(1) , 256-67, (2015)]

Hemagglutinin-based polyanhydride nanovaccines against H5N1 influenza elicit protective virus neutralizing titers and cell-mediated immunity.

2015-01-01

[Int. J. Nanomedicine 10 , 229-43, (2015)]

Protease inhibitor reduces airway response and underlying inflammation in cockroach allergen-induced murine model.

2015-04-01

[Inflammation 38(2) , 672-82, (2015)]

More Articles...