Chemical Communications 2002-07-07

A screening system for enantioselective enzymes based on differential cell growth.

Manfred T Reetz, Carsten J Rüggeberg

Index: Chem. Commun. (Camb.) (13) , 1428-9, (2002)

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Abstract

The esterase-catalyzed enantioselective hydrolysis of the fluoroacetate of pantolactone leads to fluoroacetic acid, a toxic compound which inhibits the growth of esterase-producing yeast; this forms the basis of an ee-assay.

Related Compounds

  • (S)-(+)-Pantolact...
  • DL-Pantolactone
  • D-(-)-Pantolacton...

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