Nucleic Acids Symposium Series 1980-01-01

Dibutyltin oxide--phenyl isocyanate system for regioselective phenylcarbamoylation of the hydroxy-groups of ribonucleosides.

Y Ishido, I Hirao, K Itoh, K Tamaki, Y Araki

Index: Nucleic Acids Symp. Ser. (8) , s7-8, (1980)

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Abstract

For partial phenylcarbamoylation of the hydroxy-groups of ribonucleosides, dibutyltin oxide--phenyl isocyanate system was found to be surperior to the bis(tributyltin) oxide--phenyl isocyanate system from the standpoint of reaction procedures including isolation of the products; the reaction was proved to occur with similar regioselectivity and to give the corresponding 5'-, 3'-, and 2'-O-phenylcarbamoyl derivatives in good yields, respectively, due to the conditions used.

Related Compounds

  • Dibutyltin oxide

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