Advanced Synthesis & Catalysis

A Modular Furanoside Thioether??Phosphite/Phosphinite/Phosphine Ligand Library for Asymmetric Iridium??Catalyzed Hydrogenation of Minimally Functionalized …

M Coll, O Pàmies, M Diéguez

Index: Coll, Mercedes; Pamies, Oscar; Dieguez, Montserrat Advanced Synthesis and Catalysis, 2013 , vol. 355, # 1 p. 143 - 160

Full Text: HTML

Citation Number: 16

Abstract

Abstract A highly modular furanoside thioether-phosphite/phosphinite/phosphine ligand library has been synthesized for the iridium-catalyzed asymmetric hydrogenation of minimally functionalized olefins. These ligands can be prepared efficiently from easily accessible D-(+)-xylose. We found that their effectiveness at transferring the chiral information in the product can be tuned by correctly choosing the ligand components. ...