Journal of Chromatography B 2008-11-01

Stereospecific analysis of sakuranetin by high-performance liquid chromatography: pharmacokinetic and botanical applications.

Jody K Takemoto, Connie M Remsberg, Jaime A Yáñez, Karina R Vega-Villa, Neal M Davies

Index: J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 875(1) , 136-41, (2008)

Full Text: HTML

Abstract

A stereospecific method for analysis of sakuranetin was developed. Separation was accomplished using a Chiralpak AD-RH column with UV (ultraviolet) detection at 288 nm. The stereospecific linear calibration curves ranged from 0.5 to 100 microg/mL. The mean extraction efficiency was >98%. Precision of the assay was <12% (relative standard deviation (R.S.D.)%), and within 10% at the limit of quantitation (0.5 microg/mL). Bias of the assay was lower than 10%, and within 5% at the limit of quantitation. The assay was applied successfully to pharmacokinetic quantification in rats, and the stereospecific quantification in oranges, grapefruit juice, and matico (Piper aduncum L.).

Related Compounds

  • Sakuranetin

Related Articles:

A nicotinic receptor-mediated anti-inflammatory effect of the flavonoid rhamnetin in BV2 microglia.

2014-10-01

[Fitoterapia 98 , 11-21, (2014)]

In vitro antileishmanial and antitrypanosomal activities of flavanones from Baccharis retusa DC. (Asteraceae).

2012-02-01

[Exp. Parasitol. 130(2) , 141-5, (2012)]

Isoprenylated flavonoid and adipogenesis-promoting constituents of Dodonaea viscosa.

2012-04-27

[J. Nat. Prod. 75(4) , 699-706, (2012)]

Induced volatiles in elicitor-treated and rice blast fungus-inoculated rice leaves.

2002-12-01

[Biosci. Biotechnol. Biochem. 66(12) , 2549-59, (2002)]

O-demethylation and sulfation of 7-methoxylated flavanones by Cunninghamella elegans.

2003-02-01

[Chem. Pharm. Bull. 51(2) , 203-6, (2003)]

More Articles...