Triazole pyrimidine nucleosides as inhibitors of Ribonuclease A. Synthesis, biochemical, and structural evaluation

V Parmenopoulou, DSM Chatzileontiadou…

Index: Bioorganic and Medicinal Chemistry, , vol. 20, # 24 p. 7184 - 7193

Full Text: HTML

Citation Number: 13

Abstract

... Bioorganic & Medicinal Chemistry. ... b Institute of Biology, Medicinal Chemistry & Biotechnology, National Hellenic Research Foundation, 48 Vas. ... Therefore, these proteins are pharmaceutical targets for the rational design of specific inhibitors to suppress their activity and hence ...

Related Articles:

Mild, versatile, and chemoselective indium (III) triflate-catalyzed deprotection of acetonides under microwave heating conditions

[Golden, Kathryn C.; Gregg, Brian T.; Quinn, John F. Tetrahedron Letters, 2010 , vol. 51, # 31 p. 4010 - 4013]

Simple method for fast deprotection of nucleosides by triethylamine-catalyzed methanolysis of acetates in aqueous medium

[Meier, Lidiane; Monteiro, Gustavo C.; Baldissera, Rodrigo A.M.; Sa, Marcus Mandolesi Journal of the Brazilian Chemical Society, 2010 , vol. 21, # 5 p. 859 - 866]

A catalytic method for chemoselective detritylation of 5′-tritylated nucleosides under mild and heterogeneous conditions using silica sulfuric acid as a recyclable …

[Khalafi-Nezhad, Ali; Parhami, Abolfath; Soltani Rad, Mohammad Navid; Zolfigol, Mohammad Ali; Zare, Abdolkarim Tetrahedron Letters, 2007 , vol. 48, # 30 p. 5219 - 5222]

Highly efficient synthesis of 2′, 3′-didehydro-2′, 3′-dideoxy-β-nucleosides through a sulfur-mediated reductive 2′, 3′-trans-elimination. From …

[Robles, Rafael; Rodriguez, Concepcion; Alvarez De Cienfuegos, Luis; Mota, Antonio J. Tetrahedron Asymmetry, 2004 , vol. 15, # 5 p. 831 - 838]

Methoxyethoxymethyl group for the protection of uracil residue in oligoribonucleotide synthesis

[Takaku, Hiroshi; Ueda, Souichi; Ito, Tsunehiko Tetrahedron Letters, 1983 , vol. 24, # 48 p. 5363 - 5366]

More Articles...