Preparation and derivatives of N-substituted glycinonitriles

RA Turner, C Djerassi

Index: Turner; Djerassi Journal of the American Chemical Society, 1950 , vol. 72, p. 3081

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Citation Number: 2

Abstract

In an earlier article2 was described a convenient preparation of N, N-dimethylglycinonitrile from dimethylamine, formaldehyde and hydrocyanic acid. Since substituted glycinonitriles were required as starting materials for some projected syntheses, the cyanomethylation procedure was extended to several secondary amines. It was found that when secondary amines other than dimethylamine were employed, particularly aromatic amines, it was ...