Organic Letters 2006-03-02

A novel route to dipeptides via noncondensation of amino acids: 2-aminoperfluoropropene as a synthon for trifluoroalanine dipeptides.

Yong Guo, Kana Fujiwara, Kenji Uneyama

Index: Org. Lett. 8(5) , 827-9, (2006)

Full Text: HTML

Abstract

2-Aminoperfluoropropene has been prepared by the Mg-promoted defluorinative N-silylation of N-p-methoxyphenyl hexafluoroacetone imine and has been employed as a synthon of trifluoroalanine for the preparation of trifluoroalanine dipeptides.

Related Compounds

  • 3,3,3-Trifluoroala...

Related Articles:

Low energy (0-10 eV) electron driven reactions in the halogenated organic acids CCl3COOH, CClF2COOH, and CF3CHNH2COOH (trifluoroalanine).

2011-09-28

[J. Chem. Phys. 135(12) , 124307, (2011)]

Crystal structure of the pyridoxal-5'-phosphate dependent cystathionine beta-lyase from Escherichia coli at 1.83 A.

1996-09-20

[J. Mol. Biol. 262(2) , 202-24, (1996)]

Characteristics of beta, beta-difluoroalanine and beta, beta, beta -trifluoroalanine as suicide substrates for Escherichia coli B alanine racemase.

1981-12-22

[Biochemistry 20(26) , 7539-46, (1981)]

Mechanism of inactivation of alanine racemase by beta, beta, beta-trifluoroalanine.

1989-01-24

[Biochemistry 28(2) , 431-7, (1989)]

Identification of the active-site residue of gamma-cystathionase labeled by the suicide inactivator beta, beta, beta-trifluoroalanine.

1982-08-03

[Biochemistry 21(16) , 3790-4, (1982)]

More Articles...