A Facile Synthesis of Carboxamides by Dehydration Condensation Between Free Carboxylic Acids and Amines Using O, O'-Di (2-pyridyl) Thiocarbonate as a …

I Shiina, K Saitoh, M Nakano, Y Suenaga…

Index: Shiina, Isamu; Saitoh, Katsuyuki; Nakano, Masakazu; Suenaga, Yoshihito; Mukaiyama, Teruaki Collection of Czechoslovak Chemical Communications, 2000 , vol. 65, # 4 p. 621 - 630

Full Text: HTML

Citation Number: 8

Abstract

Abstract Carboxamides are prepared in high yields by dehydration condensation between nearly equimolar amounts of free carboxylic acids and amines both of which involve secondary or tertiary alkyl substituted ones with O, O'-di (2-pyridyl) thiocarbonate, a coupling reagent, in the presence of a catalytic amount of 4-(dimethylamino) pyridine.

Related Articles:

Diphosphorus tetraiodide as a new mild condensing agent for the synthesis of amides.

[Suzuki, Hitomi; Tsuji, Junko; Sato, Naofumi; Osuka, Atsuhiro Chemistry Letters, 1983 , p. 449 - 452]

2-Arylallyl as a new protecting group for amines, amides and alcohols

[Barluenga, Jose; Fananas, Francisco J.; Sanz, Roberto; Marcos, Cesar; Ignacio, Jose M. Chemical Communications, 2005 , # 7 p. 933 - 935]

An improved modification of Ritter reaction

[Martinez, A. Garcia; Alvarez, A. Martinez; Vilar, E. Teso; Fraile, A. Garcia; Hanack, M.; Subramanian, L. R. Tetrahedron Letters, 1989 , vol. 30, # 5 p. 581 - 582]

Copper-catalyzed oxidative desulfurization–oxygenation of thiocarbonyl compounds using molecular oxygen: an efficient method for the preparation of oxygen …

[Shibahara, Fumitoshi; Suenami, Aiko; Yoshida, Atsunori; Murai, Toshiaki Chemical Communications, 2007 , # 23 p. 2354 - 2356]

2-Arylallyl as a new protecting group for amines, amides and alcohols

[Barluenga, Jose; Fananas, Francisco J.; Sanz, Roberto; Marcos, Cesar; Ignacio, Jose M. Chemical Communications, 2005 , # 7 p. 933 - 935]

More Articles...