Journal of Organic Chemistry 2001-09-21

First synthesis of lower-rim-substituted aryl ethers of p-tert-butylcalix[4]arene.

S Chowdhury, P E Georghiou

Index: J. Org. Chem. 66(19) , 6257-62, (2001)

Full Text: HTML

Abstract

With the use of S(N)Ar or Ullmann reactions, the synthesis of the first lower-rim aryl ether derivatives of tert-butylcalix[4]arene is reported, as are some of their conformational properties, (1)H NMR spectra, and X-ray crystal structures. The lower-rim aryl pendants reported herein provide for new scaffolds upon which a host of other new molecular architectures can be constructed, thus extending the capability of the versatile calix[4]arenes even further.

Related Compounds

  • 4-Fluoro-3-nitrobe...

Related Articles:

Synthesis and adrenergic activity of ring-fluorinated phenylephrines.

1986-10-01

[J. Med. Chem. 29(10) , 1982-8, (1986)]

Synthesis of beta-hydroxy-beta-(fluoronitrophenyl)alanines: vital components in the assembly of biologically active cyclic peptides.

1999-07-29

[Org. Lett. 1(2) , 295-7, (1999)]

Solid phase synthesis of vancomycin mimics. Arnusch CJ and Pieters RJ.

[European J. Org. Chem. 2003(16) , 3131-3138, (2003)]

More Articles...