The Journal of Organic Chemistry

Antineoplastic agents. 58. Synthesis of 3-aryl-5-bromo-2 (5H)-furanones

MT Edgar, GR Pettit, TH Smith

Index: Edgar,M.T. et al. Journal of Organic Chemistry, 1978 , vol. 43, # 21 p. 4115 - 4120

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Citation Number: 7

Abstract

(sloyli'. 2, 6-diphenyl-4-pyranon containing very dilute methoxide ion. Under this aspect, the tendency of pyrylium cations to undergo nucleophilic addition seems qualitatively higher than that of pyridinium cations under similar conditions. Z1 Further work will be necessary in order to assess quantitatively this tendency. The possibility of rapid interconversions between the reaction products (isomeric pyrans and/or dienones) has some implication on ...