Synlett

Lewis Acid-Catalyzed Reductive Amination of Carbonyl Compounds with Aminohydrosilanes

K Miura, K Ootsuka, S Suda, H Nishikori, A Hosomi

Index: Miura; Ootsuka; Suda; Nishikori; Hosomi Synlett, 2001 , # 10 p. 1617 - 1619

Full Text: HTML

Citation Number: 16

Abstract

Abstract: The TiCl4-catalyzed reaction of aromatic carbonyl compounds with (dialkylamino) dimethylsilanes gave tertiary amines in moderate to high yields. The reductive amination of aliphatic aldehydes was effectively catalyzed by ZnI2. Methyl N-(dimethylsilyl) carbamate as well could be used for reductive amination of carbonyl compounds in the presence of Ph3CClO4. Key words: Lewis acids, reductive aminations, amines, aldehydes, ...

Related Articles:

Ruthenium-catalyzed N-alkylation of amines and sulfonamides using borrowing hydrogen methodology

[Hamid, M. Haniti S. A.; Allen, C. Liana; Lamb, Gareth W.; Maxwell, Aoife C.; Maytum, Hannah C.; et al. Journal of the American Chemical Society, 2009 , vol. 131, p. 1766 - 1774]

New synthetic route to pheniramines via hydroformylation of functionalyzed olefins

[Journal of Organic Chemistry, , vol. 59, # 23 p. 7125 - 7127]

Dual Si–H effects in platinum-catalyzed silane reduction of carboxamides leading to a practical synthetic process of tertiary-amines involving self-encapsulation of the …

[Tetrahedron Letters, , vol. 47, # 35 p. 6173 - 6177]

Synthesis and evaluation of novel alkylpiperazines as potential dopamine antagonists

[Glennon; Salley Jr.; Steinsland; Nelson Journal of Medicinal Chemistry, 1981 , vol. 24, # 6 p. 678 - 683]

Sommelet-Hauser Rearrangement of Allylbenzyldimethylammonium Bromide and Cyclopropylcarbinylbenzyldimethylammonium Bromide. Evidence for Carbanion …

[Journal of the American Chemical Society, , vol. 85, p. 73 - 78]

More Articles...