Catalysis today

Biocatalytic reduction of α-keto amides to (R)-α-hydroxy amides using Candida parapsilosis ATCC 7330

S Stella, A Chadha

Index: Stella, Selvaraj; Chadha, Anju Catalysis Today, 2012 , vol. 198, # 1 p. 345 - 352

Full Text: HTML

Citation Number: 12

Abstract

Biocatalytic reduction of primary and secondary α-keto amides was accomplished using whole cells of Candida parapsilosis ATCC 7330. The primary (R)-α-hydroxy amides were obtained in good enantiomeric excess (up to 94%) and conversion (88–99%) as compared to the secondary (R)-α-hydroxy amides.

Related Articles:

A straightforward synthesis of N-monosubstituted α-keto amides via aerobic benzylic oxidation of amides

[Shao, Jun; Huang, Xiaomei; Wang, Siyuan; Liu, Bingxin; Xu, Bin Tetrahedron, 2012 , vol. 68, # 2 p. 573 - 579]

Preparation of some stable and transient 1, 3-oxazolium-4-olates

[Haddadin, Makhluf J.; Tannus, Hana T. Heterocycles, 1984 , vol. 22, # 4 p. 773 - 778]

A simple, efficient, regioselective and one-pot preparation of N-hydroxy-and N–O-protected hydroxyindoles via cycloaddition of nitrosoarenes with alkynes. Synthetic …

[Ieronimo, Gabriella; Mondelli, Alessandro; Tibiletti, Francesco; Maspero, Angelo; Palmisano, Giovanni; Galli, Simona; Tollari, Stefano; Masciocchi, Norberto; Nicholas, Kenneth M.; Tagliapietra, Silvia; Cravotto, Giancarlo; Penoni, Andrea Tetrahedron, 2013 , vol. 69, # 51 p. 10906 - 10920]

Amidophosphine-Phosphinites: Synthesis and Use in Rhodium-Based Asymmetric Hydrogenation of Activated Keto Compounds. Crystal Structure of Bis [(μ-chloro)((S …

[Tani, Kazuhide; Suwa, Kenichi; Tanigawa, Eiji; Ise, Tomokazu; Yamagata, Tsuneaki; et al. Journal of Organometallic Chemistry, 1989 , vol. 370, p. 203 - 222]

Reaction of 4??aryl??1, 2, 4??triazines with hydrazine

[Ibrahim, Y. A.; Eid, M. M.; Badawy, M. A.; Abdel-Hady, S. A. L. Journal of Heterocyclic Chemistry, 1981 , vol. 18, p. 953 - 956]

More Articles...