Decreased circulating lipoprotein-associated phospholipase A2 levels are associated with coronary plaque regression in patients with acute coronary syndrome

Tomotaka Dohi, Katsumi Miyauchi, Shinya Okazaki, Takayuki Yokoyama, Ryunosuke Ohkawa, Kazuhiro Nakamura, Naotake Yanagisawa, Shuta Tsuboi, Manabu Ogita, Ken Yokoyama, Takeshi Kurata, Yutaka Yatomi, Hiroyuki Daida

Index: Atherosclerosis 219 , 907, (2011)

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Abstract

Objective Lipoprotein-associated phospholipase A2 (Lp-PLA2) is a vascular-specific inflammatory enzyme, of which increases are associated with cardiovascular events. However, the relationship between circulating Lp-PLA2 levels and coronary plaque volume has not been clarified in patients with acute coronary syndrome (ACS).