Synthese de dihydro-6, 7 5H-pyrimidino (5, 4-c) carbazoles et de 7H-pyrimidino (5, 4-c) carbazoles.

JC LANcELoT, JM GAzENGEL…

Index: Lancelot, Jean-Charles; Gazengel, Jean-Marie; Robba, Max Chemical & Pharmaceutical Bulletin, 1983 , vol. 31, # 8 p. 2652 - 2661

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Citation Number: 11

Abstract

The synthesis of 6, 7-dihydro-5H-pyrimidino [5, 4-c] carbazoles (3) was achieved by cyclisation of 1, 2, 3, 4-tetrahydrocarbazol-4-ones with triformamidomethane. The oxydation with potassium permanganate of 6, 7-dihydro-5H-pyrimidino [5, 4-c] carbazoles gave the 7H- pyrimidino [5, 4-c] carbazoles (4). The reactions of the pyrimidinocarbazoles (4a) and (4e) with lithium organic compounds afforded 4-substituted derivatives (6). The structure of the ...

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