Synthesis of new quinoline fused heterocycles such as benzo [h]-1, 6-naphthyridines and pyrazolo [4, 3-c] quinolines

BK Ghotekar, MG Ghagare, RB Toche…

Index: Ghotekar, Bhausaheb Kedarnath; Ghagare, Maruti G.; Toche, Raghunath B.; Jachak, Madhukar N. Monatshefte fur Chemie, 2010 , vol. 141, # 2 p. 169 - 175

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Citation Number: 20

Abstract

Abstract Synthesis of novel benzo [h]-1, 6-naphthyridines was successfully achieved by cyclocondensation of ethyl 4-aminoquinoline-3-carboxylates with malononitrile. The pyrazolo [4, 3-c] quinolines were synthesized by nucleophilic substitution and subsequent addition reaction of ethyl 4-chloroquinoline-3-carboxylates with different hydrazines. All new compounds were characterized by spectral and analytical methods. Graphical abstract