Research in Veterinary Science 1989-05-01

Colorimetric assay for the detection of benzimidazole resistance in trichostrongyles.

I A Sutherland, D L Lee, D Lewis

Index: Res. Vet. Sci. 46(3) , 363-6, (1989)

Full Text: HTML

Abstract

A modified version of the aphid tile-test, which is used to detect insecticide resistance in single adult aphids that are resistant or susceptible to organophosphate or carbamate insecticides, was used to compare the levels of non-specific esterases in strains of the trichostrongyle nematodes Haemonchus contortus, Ostertagia circumcincta and Trichostrongylus colubriformis which were known to be resistant or susceptible to benzimidazole (BZ) anthelmintics. This colorimetric assay has shown that there is significantly more non-specific esterase in the infective-stage larvae of BZ-resistant strains than in susceptible strains and this may prove to be of use in the detection of resistance to benzimidazole anthelmintics.

Related Compounds

  • Cambendazol

Related Articles:

The Hymenolepis diminuta-golden hamster (Mesocricetus auratus) model for the evaluation of gastrointestinal anticestode activity.

2004-08-01

[J. Parasitol. 90(4) , 898-9, (2004)]

Structural requirements for the induction of cytochromes P450 by benzimidazole anthelmintic derivatives in cultured rabbit hepatocytes.

1996-03-27

[Biochem. Biophys. Res. Commun. 220(3) , 789-94, (1996)]

Controlled tests of activity of several antiparasitic compounds against natural infections of Haemonchus contortus and other helminths in lambs from a flock established in 1962.

1993-03-01

[Am. J. Vet. Res. 54(3) , 406-10, (1993)]

Haemonchus contortus: the role of two beta-tubulin gene subfamilies in the resistance to benzimidazole anthelmintics.

1994-04-29

[Biochem. Pharmacol. 47(9) , 1705-15, (1994)]

Control of cambendazole-resistant small strongyles (Population S) with oxibendazole in a pony band: an 8 year field test (1984-1992).

1994-04-01

[Vet. Parasitol. 52(3-4) , 271-7, (1994)]

More Articles...