Tetrahedron

Syntheses of some tetralones related to tetracyclines

A Bhati

Index: Bhati,A. Tetrahedron, 1962 , vol. 18, p. 1519 - 1526

Full Text: HTML

Citation Number: 7

Abstract

Syntheses of 5-chloro-8-methoxy-1-tetralone (XIV), 6, 8-dimethoxy-1-tetralone (XIX), 2- carbethoxy-6, 8-dimethoxy-1-tetralone (VI), 3-(2′-chloro-5′-methoxybenzyl)-6, 8- dimethoxy-1-tetralone (III) and 2-carbethoxy-3-(2′-chloro-5′-methoxybenzyl)-6, 8- dimethoxy-1-tetralone (IV) are reported. The mode of cyclization with polyphosphoric acid of I and related compounds is described.

Related Articles:

Cubyl amides: novel P2X 7 receptor antagonists

[Gunosewoyo, Hendra; Guo, Jun Liu; Bennett, Maxwell R.; Coster, Mark J.; Kassiou, Michael Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 13 p. 3720 - 3723]

Total synthesis of tetracyclines. 1 III. 2 synthesis of a tricyclic model system

[Wilkinson,R.G. et al. Journal of Organic Chemistry, 1961 , vol. 26, p. 637 - 643]

More Articles...