Synthesis

Zinc mediated friedel-crafts acylation in solvent-free conditions under microwave irradiation

S Paul, P Nanda, R Gupta, A Loupy

Index: Paul, Satya; Nanda, Puja; Gupta, Rajive; Loupy, Andre Synthesis, 2003 , # 18 p. 2877 - 2881

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Citation Number: 42

Abstract

Abstract Zn powder is found to catalyze the Friedel-Crafts acylation of aromatic compounds with acyl halides efficiently under microwave irradiation in solvent-free conditions. Activated substrates undergo acylation predominantly at the para-position. The Zn powder can be re- used up to six times after simple washing with diethyl ether and dilute HCl.

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