Chemotherapeutic Nitrofurans. I. Some Derivatives of 3-Amino-2-oxazolidone1

G Gever, C O'Keefe, G Drake, F Ebetino…

Index: Gever et al. Journal of the American Chemical Society, 1955 , vol. 77, p. 2277,2280, 2281

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Citation Number: 10

Abstract

A number of 3-amino-2-oxazolidones have been prepared by the cyclization of 2-(2- hydroxyalkyl)-semicarbazides with hydrochloric acid, the condensation of P-hydrazino alcohols with some carbonic acid esters and chlorides and the catalytic or electrolytic reduction of 3-nitro-2-oxazolidones. These 3-amino-2-oxazolidone have been converted to chemotherapeutically active 5-nitro-2-acylfuran derivatives.