Reactions of arylmethanethiols with 1, 4-disubstituted 1, 3-butadiynes

F Freeman, H Lu, Q Zeng…

Index: Freeman, Fillmore; Lu, Hengyao; Zeng, Qingbei Journal of Organic Chemistry, 1994 , vol. 59, # 15 p. 4350 - 4354

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Citation Number: 25

Abstract

Owing to our interest in the synthesis and bioactivity of 1, 2-dithiacyclohexa-3, 5-dienes [l, Pdithiins, eg. thiarubrine A (1) and thiarubrine B (2) 1, we are investigating the reactions of thiols with enediynes, polyenynes, and polyalkynes under various experimental Efficient syntheses of a wide variety of natural and unnatural 1, 2-dithiins2-11 and a study of structureactivity relationships (SAR) will help in gaining a better understanding of the ...