Cross-resistance to medical and agricultural azole drugs in yeasts from the oropharynx of human immunodeficiency virus patients and from environmental Bavarian vine grapes.

Frank-Michael C Müller, Andrea Staudigel, Stefanie Salvenmoser, Antje Tredup, Rudolf Miltenberger, Josef V Herrmann

Index: Antimicrob. Agents Chemother. 51 , 3014-6, (2007)

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Abstract

Cross-resistance among Candida albicans isolates from the oropharynges of human immunodeficiency virus-infected patients (n = 16) and environmental yeast strains of various species (n = 54) to medical and agricultural azole drugs was observed. Precautions against the unnecessary widespread use of azoles in the environment and human medicine are strongly recommended to prevent patients from acquiring azole-resistant yeasts.