Analyst (Cambridge UK) 2016-02-07

Synthesis and characterization of a multimode stationary phase: Congo red derivatized silica in nano-flow HPLC.

Yi Zhang, Yan Zhang, Guan Wang, Wujuan Chen, Pingang He, Qingjiang Wang

Index: Analyst 141 , 1083-90, (2016)

Full Text: HTML

Abstract

A novel Congo red (CR) derivatized silica stationary phase was prepared and packed into a fused silica capillary tube for nano-flow HPLC. A variety of analytes including poly-aromatic hydrocarbons, parabens, acids, sulfonamides, bases, and nucleosides were successfully separated using the CR. In comparison with commercial ODS columns, this new stationary phase has a different separation mechanism (hydrophobically-assisted ion-exchange), which was evident in the separation of benzoic acid derivatives and sulfonamides. The successful application of CR-bonded silica stationary phase in the HILIC and PALC modes demonstrates the effectiveness of this potential chromatographic material in nano flow HPLC.

Related Compounds

  • germane
  • 2'-Deoxycytidine-5...
  • Uridine monophosph...

Related Articles:

Solid lipid nanoparticles for hydrophilic biotech drugs: optimization and cell viability studies (Caco-2 & HEPG-2 cell lines).

2014-06-23

[Eur. J. Med. Chem. 81 , 28-34, (2014)]

The biocompatibility of degradable magnesium interference screws: an experimental study with sheep.

2015-01-01

[Biomed Res. Int. 2015 , 943603, (2015)]

Ligand-engaged TCR is triggered by Lck not associated with CD8 coreceptor.

2014-01-01

[Nat. Commun. 5 , 5624, (2014)]

Fabrication of novel magnetic nanocomposite with a number of adsorption sites for the removal of dye.

2015-01-01

[Int. J. Biol. Macromol. 78 , 17-22, (2015)]

Rapid evaluation and comparison of natural products and antioxidant activity in calendula, feverfew, and German chamomile extracts.

2015-03-13

[J. Chromatogr. A. 1385 , 103-10, (2015)]

More Articles...