Synthesis of substituted 4 (Z)-(methoxyimino) pentyl-1-piperidines as dual NK 1/NK 2 inhibitors

…, JF Lee, JC Anthes, NY Shih, JJ Piwinski

Index: Ting, Pauline C; Lee, Joe F; Anthes, John C; Shih, Neng-Yang; Piwinski, John J Bioorganic and Medicinal Chemistry Letters, 2001 , vol. 11, # 4 p. 491 - 494

Full Text: HTML

Citation Number: 21

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... The NK 1 and NK 2 receptor activity of a series of 5-[(3,5-bis(trifluoromethyl)phenyl)methoxy]-3-(3,4-dichlorophenyl )-4(Z)-(methoxyimino)pentyl-1-piperidines was evaluated. Compounds 11d, 11e, 11f, 12a, and 12k were found to be our most potent inhibitors. ... A series of 4(Z)-(methoxyimino)pentyl- ...

Related Articles:

Synthesis of substituted 4 (Z)-(methoxyimino) pentyl-1-piperidines as dual NK 1/NK 2 inhibitors

[Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 4 p. 491 - 494]

Synthesis of substituted 4 (Z)-(methoxyimino) pentyl-1-piperidines as dual NK 1/NK 2 inhibitors

[Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 4 p. 491 - 494]

Synthesis of substituted 4 (Z)-(methoxyimino) pentyl-1-piperidines as dual NK 1/NK 2 inhibitors

[Bioorganic and Medicinal Chemistry Letters, , vol. 11, # 4 p. 491 - 494]

More Articles...