Chemosphere 2006-06-01

Occurrence and photochemical degradation of 17alpha-ethinylestradiol in Acushnet River Estuary.

Yuegang Zuo, Kai Zhang, Yiwei Deng

Index: Chemosphere 63(9) , 1583-90, (2006)

Full Text: HTML

Abstract

17alpha-Ethinylestradiol (EE2), a major constituent of common contraceptive pills, and three other estrogenic hormones, estrone (E1), 17beta-estradiol (E2) and mestranol (MeEE2) have been determined in Acushnet River Estuary seawater using a GC-MS technique. Among three estrogenic compounds detected, EE2 has the highest concentration, up to 4.7 ng/l, at which EE2 may affect lobster and other fish abundance in the coastal seawater due to its high biological activity on fish feminization. Two natural estrogenic hormones, E1 and E2 have also been found in the estuary at concentrations up to 1.2 ng/l and 0.83 ng/l, respectively. Although EE2 is persistent to microbial degradation, it can undergo a rapid photodegradation in estuarine seawater under natural sunlight irradiation, with a half-life of less than 1.5 days in spring sunny days.


Related Compounds

  • mestranol

Related Articles:

Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.

2010-01-01

[Chem. Res. Toxicol. 23 , 171-83, (2010)]

Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

2011-12-01

[J. Sci. Ind. Res. 65(10) , 808, (2006)]

Developing structure-activity relationships for the prediction of hepatotoxicity.

2010-07-19

[Chem. Res. Toxicol. 23 , 1215-22, (2010)]

A predictive ligand-based Bayesian model for human drug-induced liver injury.

2010-12-01

[Drug Metab. Dispos. 38 , 2302-8, (2010)]

Extending an in vitro panel for estrogenicity testing: the added value of bioassays for measuring antiandrogenic activities and effects on steroidogenesis.

2014-09-01

[Toxicol. Sci. 141(1) , 78-89, (2014)]

More Articles...