Ortho selectivity in SN Ar substitutions of 2, 4-dihaloaromatic compounds. Reactions with piperidine

MD Wendt, AR Kunzer

Index: Tetrahedron Letters, , vol. 51, # 4 p. 641 - 644

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Citation Number: 13

Abstract

... Tetrahedron Letters. Volume 51, Issue 4, 27 January 2010, Pages 641–644. Cover image Cover image. ... A comparison of F and Cl as leaving groups (1b vs 4, 8 vs 9, 10 vs 11, 12 vs 13), indicates that Cl tends to favor ortho-substitution relative to F, albeit by a small amount. ...